4. Without Papal influence, the family fell into decline
Cesare fell on hard times as soon as Pope Alexander VI died, and others didn’t fare well either. In fact, after the death of Lucrezia, the whole Borgia family went into steady decline. Lucrezia’s marriage to Alfonso d’Este protected her from the many Borgia enemies, but subsequent generations weren’t so lucky. They hardly lived impoverished lives but never reached the pinnacle of power that Alexander and his children managed. Without a scheming, corrupt Pope on their side, later generations were at the mercy of other powerful Machiavellian figures. By the middle of the 18th century, the Borgias were extinct.